An ecosystem of startups born from the talent and expertise developed at Politecnico di Milano, now active in key innovation sectors and founded by students, alumni and researchers. Politecnico di Milano provides an environment that connects education, research and industry, fostering entrepreneurial growth and access to the market. A dynamic and constantly evolving ecosystem, capable of attracting investment, fostering collaborations with companies and institutions, and developing key skills to generate innovation in strategic sectors.
In 2026, 50 startups originating from the Politecnico di Milano ecosystem were officially recognised.
Business and Innovation Stories
Every startup is born from a unique entrepreneurial journey, shaped by the vision of its founders, who combine technical expertise, creativity and vision to develop innovative solutions for the market. Through a selection of stories, we explore how some of the Politecnico di Milano’s startups came to life: from the initial idea to product development and growth.
Interview with the founders
Displaid
Scalable AI- and smart sensor-based solution for predictive monitoring of bridges and infrastructure.
Interview with the founders
GeospatialX
Geospatial intelligence infrastructure that integrates heterogeneous data sources and enables users to query assets, portfolios, and territories in natural language.
Our Startups
All innovative startups established with the support of Politecnico di Milano.
Smart roadside device that converts the kinetic energy dissipated by vehicles during braking/deceleration into electricity (“Lybra” technology).
Thin-film electroadhesive technology for robotic manipulation (grasping) in industrial and space applications, without magnets or compressors.
Designs, implements and deploys cloud, IoT and Big Data solutions, integrating complex systems and platforms.
Software house developing custom enterprise solutions for companies with complex requirements.
Digital platform that helps individuals and SMEs estimate real-time savings on electricity, gas, internet and telecommunications, using AI and OCR.
Develops WaterCube, an innovative water-based propulsion unit for CubeSats and small satellites.
Deep-tech company providing customer profiling solutions for financial institutions and retailers using AI and neural networks.
Scalable AI-powered solution using smart sensors for predictive monitoring of bridges and infrastructure.
Develops a software-based model for sustainable space operations; its first product (SAFE) prevents collisions in orbit.
“Electrokinetic In Situ Recovery” (EK-ISR) mining technology for extracting metals through a 100% electric process, without excavation or rock fracturing.
They enable organizations to reduce energy consumption and maximize uptime and productivity through an AI-based, expert-driven solution with a rapid return on investment.
Develops HyperDart, a reusable and sustainable launch vehicle for small satellites capable of taking off from conventional runways.
Develops autonomous electric airships (helium-filled and solar-powered) for long-range environmental and infrastructure monitoring, as an alternative to drones and helicopters.
Fraido S.r.l. is an early-stage Italian MedTech startup developing an innovative endotracheal intubation device with continuously adjustable diameter, designed to make the procedure safer and easier while reducing complications and costs for healthcare systems.
Innovative software for graph-based genomic analysis (graph genomics).
Electrochemical device combined with AI algorithms that detects traces of gluten in food, including cooked food, in real time, for the food service and food industry sectors.
Portable, quick-to-assemble emergency shelter designed to provide home-like comfort in times of greatest need.
Develops FPGA-based hardware acceleration solutions for artificial intelligence and deep learning applications, as a spin-off of NECSTLab at the Politecnico di Milano.
Next-generation wind turbines with an active airflow control system to increase efficiency.
Software platform supporting decision-making for professional football clubs, integrating data from all departments across the organization (prototyped at PoliHub and later founded in the United Kingdom).
Patented technology for removing carbon from the atmosphere in the form of bicarbonates.
Lizard offers Furniture-as-a-Service solutions for Interior Design, Property Management, and the commercial real estate sector. We provide catalogues of sustainable, configurable furniture, including professional installation, maintenance, and insurance. At the end of the contract, we take care of furniture collection, refurbishment, and recycling, ensuring flexibility, efficiency, and compliance with ESG criteria.
Artificial intelligence system for monitoring access and movement in elderly care.
Scheduled home delivery service that allows customers to choose the day and a 30-minute time window for receiving their parcels.
Develops neuromorphic processors capable of simulating how the human brain works.
Applies artificial intelligence to oncology; founded in the United States (Y Combinator, Summer 2025 batch).
Overspace Aviation manufactures high-performance VTOL aircraft (e.g. Dragonfly DS-1) with a modular, patented design.
Hardware/software platform with a robotic probe for the inspection and predictive maintenance of pipelines used to transport liquids and gases.
Low-carbon construction materials that maintain the performance of traditional solutions.
Space startup (founded by Marco Sala and Filippo Oggionni) active in the development of hardware and satellites, with an orbital launch in 2025.
Dispositivo portatile di imaging medicale per rilevare e quantificare fluidi non visibili con le tecniche tradizionali.
Long-duration energy storage technology based on pumped hydro.
Cloud-native access control system based on IoT and smartphones for the digital management of locks and access points in buildings.
Wireless energy transmission via laser for remote charging, for example of drones.
The core technology developed by TALPA-Inspection consists of a patented contactless electrochemical sensor technology for mapping and detecting corrosion in reinforced concrete. [1, 2]
AI- and satellite data (Earth Observation)-based service to identify optimal land for viticulture and monitor vineyards with a view to climate change adaptation.
Vepartment S.r.l. is a Milan-based startup that develops an AI-powered software platform for managing virtual corporate departments.
Transceivers for CubeSats and small satellites, designed to facilitate communication within large commercial satellite constellations.
Lightweight, efficient structural batteries for extreme applications (e.g. aerospace).
B2B platform for circular fashion that upcycles unused or waste textile and high-value materials.